产品货号：
Z37709
中文名称：
GABAB R1a Purified抗体
英文名称：
Anti-GABAB R1a Purified Antibody (Clone#PAb (549))
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GABAB R1a Purified Antibody (Clone#PAb (549)) |
| 指标别名 | gamma-aminobutyric acid type B receptor subunit 1;GABABR1-3;GB1;GPRC3A;GABBR1 |
| 克隆性 | Monoclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,ICC |
| 基因名称 | GABBR1 |
| 克隆号 | PAb (549) |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthetic peptide (coupled with THG) derived from aminoacid sequence 100-124 of mouse GABA B receptor 1.The sequence has 100% homology with rat and human.The polyclonal antibody recognizes N-terminus of mouse gamma-aminobutyric acid (GABA) B receptor 1a.GB1a apparent MW~130kDa. |
| 计算分子量 | 112kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | GABA B receptor is a G-protein-coupled inhibitory receptor of gamma-aminobutyric acid (GABA),and has important functions in brain by inhibition of adenylyl cyclase and modulation of G-protein-gated Ca2+ and K+ channels.GABA B receptor is comprised of two subunits,GB1 and GB2 with N-terminal extracellular and C-terminal intracellular domains.The GB1 subunit plays a critical role in ligand binding,whereas the GB2 subunit contains the determinants required for G-protein signaling.Multiple allosteric interactions between the two subunits are required for correct functioning of the receptor.There are two N-terminal splice variants of GB1 subunit,termed GB1a and GB1b;their expression in the central nervous system changes during the ontogenesis and differs between various regions of the brain. |
| Uniprot ID | Q9Z0U4 |
| 基因名全称 | Gamma-aminobutyric acid type B receptor subunit 1 |
| 蛋白名全称 | Gamma-aminobutyric acid type B receptor subunit 1 |
相关搜索：GABAB R1a Purified抗体，GABAB R1a Purified)单抗